02080nas a2200265 4500000000100000008004100001100001100042700001100053700001300064700001600077700001700093700001600110700001700126700002200143700001300165700002900178700001800207700001300225700001300238245004300251300001000294490000700304520148900311022001401800 2018 d1 aJha V.1 aZuo Li1 aTeo Boon1 aZhang Luxia1 aGuh Jinn-Yuh1 aTang Sydney1 aKang Duk-Hee1 aTanchanco Roberto1 aHooi Lai1 aPraditpornsilpa Kearkiat1 aKong Xianglei1 aChan Gek1 aLee Evan00aGlomerular Filtration Rates in Asians. a41-480 v253 a

The National Kidney Foundation Kidney Disease Outcomes Quality Initiative guidelines recommended the Modification of Diet in Renal Disease study equation for estimating glomerular filtration rate (GFR) for the classification of CKD, but its accuracy was limited to North American patients with estimated GFR <60 mL/min per 1.73 mbody surface area of European (White) or African (Black) descent. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) developed another equation for estimating GFR, derived from a population that included both participants without kidney disease and with CKD. But many ethnicities were inadequately represented. The International Society of Nephrology, Kidney Disease Improving Global Outcomes committee promulgated clinical practice guidelines, which recommended the CKD-EPI equation. Investigators in Asia subsequently assessed the performance of these GFR estimating equations-the Modification of Diet in Renal Disease study equation, the CKD-EPI equation (creatinine only), and the CKD-EPI equations (creatinine and cystatin C). In this review, we summarize the studies performed in Asia on validating or establishing new Asian ethnicity GFR estimating equations. We included both prospective and retrospective studies which used serum markers traceable to reference materials and focused the review of the performance of GFR estimation by comparisons with the GFR estimations obtained from the CKD-EPI equations.

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